One-Stop ADC
CDMO Service
ChemExpress offers integrated services spanning from Payload-Linker to ADC DS&DP, enabling efficient scale-up and seamless technology transfer, effectively reducing management and transition costs.
Extensive Project Experience
& Comprehensive Inventory
Over 80 CMC projects, 6 BLA projects, and 1 commercial project have been delivered. 16 ADC payloads and related intermediates are registered with the FDA as DMFs.
Expert Scientific
Team
Our team of over 700 scientists provides comprehensive support from R&D to commercialization, ensuring high-quality, scalable solutions for your ADC pipeline.
Our Services
Our ADC manufacturing platform is designed to accommodate diverse production needs while consistently delivering high-quality, globally compliant ADC products.
Our Service Scope Includes
ADC DS GMP Manufacturing
- OEB-5 isolator, adapted to a wide range of ADC conjugation processes
- 5L, 20L, 50 L, 100 L, 200 L, 500 L disposable/glass/stainless-steel conjugation reactors, 1 conjugation line (Reserve space for 4 lines)，0.5-5 kg/batch
- Annual Design Capacity: 300 batches; Annual throughput: 1,500 kg
ADC DP GMP Manufacturing
- 1 ADC filling line: 10 m2 and 25 m2 lyophilizers
- 2 ml, 6 ml, 10 ml, 20 ml, 50 ml and full specification of aqueous injection and lyophilization isolators
- Annual Production Capacity: 5 million bottles, Annual output: 50 batches
Why Partner with ChemExpress
Different Scales of Conjugation Reactors
Equipped with 5L, 20L, 50 L, 100 L, 200 L and 500 L process development conjugation reactors and 5 GMP production lines, enabling production from milligram to kilogram scale with an annual capacity of up to 1,500 kg Process robustness and scale-up consistency have been validated across different volumes
Multi-Scale GMP Antibody Manufacturing Flexibility
Flexible and multi-functional antibody manufacturing lines with modular design allowing parallel operation at 200 L, 500 L, and 2,000 L scales within a unified GMP framework for efficient scale transition.
Customized Formulation Production
Equipped with 1 ADC filling line, including 10㎡ and 25㎡ freeze-dryers, with fully equipped lines for 2 ml, 6 ml, 10 ml, 20 ml and 50 ml aqueous injections and lyophilized, ensuring timely delivery.
Our Sites
R&D Site & Manufacturing Site
Manufacturing Site
XDC DS&DP Process Development and Manufacturing
Related Services
ADC Payload Linker
We specialize in complex and novel Payload-Linker, offering fully customized synthesis services to meet the specific needs of client projects.
ADC Conjugation
At ChemExpress, our expert team offers flexible and scalable ADC conjugation solutions covering both site-specific and non-site-specific technologies.
ADC Drug Substance Process Development
Partner with ChemExpress for cutting-edge, efficient ADC drug substance process development, from payload-linker synthesis to conjugation.
ADC Formulation Development
We align your pipeline with your preferred target product profile (TPP) through a comprehensive range of formulation development services, including aqueous injections and lyophilized formulations.
ADC Manufacturing
We provide cGMP-compliant bioconjugate manufacturing services for R&D, clinical and commercial stages, covering the entire ADC production process.
ADC Analytical Development & Quality Control
We are committed to offering complete analytical services for ADC drug development, covering key aspects like structural characterization, impurity analysis, microbial safety control , and stability study.
FAQs
We can develop and manufacture CHO cell-expressed recombinant proteins under GMP conditions.
All ADC samples delivered by ChemExpress are processed through sterile filtration and endotoxin removal, ensuring that the final material meets sterility and low-endotoxin requirements.
Yes. ChemExpress provides end-to-end ADC services, covering non-GMP process development, GMP clinical manufacturing, and commercial supply readiness.
Our facilities are designed to support smooth transition from early development to GMP production, with dedicated ADC suites, single-use systems, and high-containment isolators up to OEB-5. This integrated approach minimizes technology transfer risks and accelerates program progression.
