• Discovery

Synthetic Chemistry

What We Offer

  • Scale up from milligrams to kg scale
    Building blocks, reference compounds, intermediates, chemical reagents, impurities, isotopic label, etc.
  • Custom synthesis services
    Small molecules of ADC, Protacs, nucleoside/nucleotide, oligonucleotide and peptide etc.

Why Partner with ChemExpress

Extensive Synthetic Experience

  • Skilled at challenging molecule synthesis : Highly experienced and qualified for syntheses of a variety of compounds and new modalities, including, but not limited to, small molecules, antibody-drug conjugates (ADC), PROTACs, peptides, and oligonucleotides.
  • Experience in structure activity relationship investigation : Current projects cover over 20 signaling pathways and hundreds of biological targets for therapeutics such as KRAS, PI3K, EGFR, and STING.

Technology Platforms

  • Modern laboratory techniques : Schlenk technique, high pressure hydrogenation, handling of explosive/hazardous compounds.
  • Enabling technology platforms : High throughput screening, continuous flow chemistry, solid phase synthesis of peptides, photoredox chemistry and isotopic labeling synthesis.

Medicinal Chemistry

What We Offer

  • Compound high throughput screening
  • Structure based drug discovery service
  • Lead compounds optimization
  • Pre-clinical drug candidates development
  • Generation of compounds for IND submission

Why Partner With ChemExpress

  • Assisted 3 clients to complete PCC development within one year
  • 3-6 compounds delivered per full-time employee (FTE) each month, and the number of reactions completed by each scientific researcher greater than 10
  • Experts at multistep synthesis and refractory problem solving(linear reactions more than 12 steps , total more than 15 steps)
  • On time delivery rate for the known target compounds >95% , and for the unknown targets >85%
  • Elite chemists SWAT TEAM
  • State-of-the-art product and data management system

Efficient Team

    Service Types
  • 10+ years
    Experience in Drug R&D
  • 3-6 Compounds
    Delivered Per Full-time Employee (FTE) Each Month