Synthetic Chemistry
What we can offer
-
Custom Synthesis ServiceBuilding blocks, reference compounds, novel chemical reagents, etc.
-
Scale upFrom milligrams to kilograms

Why Partner With ChemExpress
Riched Synthesis Experience
-
Skilled at tackling complex synthetic routes : experienced in the synthesis of a variety of reference compounds, small molecules for antibody-drug conjugates (MMAE Exatecan, Eribulin, etc.), and PROTACS
-
Structure modification of target-related compounds : including over 20 signaling pathwaysand hundreds of targets for therapeutics, such as KRAS, PI3K, Bcl-2, HDAC, BET, CDK, JAK, ERK, EGFR, PD-1/PD-L1, GSK-3, STING, etc.
Enabling Technolgies
-
Complex chemical technology : anhydrous and oxygen-free operation, high pressure hydrogenation operation, operation of hazardous compounds such as diazomethane, etc.
-
Multiple chemical technology platforms : high-throughput catalyst selection, continuous flow chemistry, multi-step coupling synthesis of amino acids, photo chemistry, isotope labeling, etc.

Medicinal Chemistry
What we can offer
-
High-throughput screening and discovery of active compounds based on structural design
-
Hit compounds discovery from DEL
-
Lead compounds optimization
-
Pre-clinical drug candidates development

Why Partner With ChemExpress
-
Assisted 3 clients to complete PCC development within one year
-
3-6 compounds delivered per full-time employee (FTE) each month, and the number of reactions completed by each scientific researcher > 10
-
Expertise at multistep synthesis and refractory problem solving(linear reactions > 12 steps , total > 15 steps)
-
On time delivery rate for the known target compounds>95% , and for the unknown targets >85%
-
Elite chemists SWAT TEAM
-
State-of-the-art laboratory information and compounds management system for product and data management

Efficient Team
-
FTE/FFSService Types
-
10+Rich Experience In Drug R&D
-
3-6 CompoundsDelivered Per Full-time Employee (FTE) Each Month