Hot Melt Extrusion

The mechanism of HME is to disperse APIs in the polymer matrix at the molecular level to form amorphous solid dispersions. Amorphous solid dispersions can improve bioavailability in more than 80% of cases. The advantage of HME technology is the capability of continuous manufacturing with solvent-less processing and friendly downstream processing of extrudates into final dosage forms (tablets, capsules, controlled release forms etc.). HME has increased use in the pharmaceutical industry.

Our Capability

Equipped with both g-scale and larger scale (throughput up to 5kg/h) equipment, we can enable screening to bulk preparation to support various clinical phases and commercialization.