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Val-Cit-PAB-MMAE

CAS:
644981-35-1

Catalog:
HY-100374

Molecular Formular:C58H94N10O12

Molecular Weight:1123.43

Description :Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a cytotoxic payload MMAE. Monomethyl Auristatin E(MMAE)  functions as a potent mitotic inhibitor by inhibiting tubulin polymerization.Valine-citrulline is a common lysosomally cleavable dipeptide.  PAB is a typical self-immolative spacer.

We can provide high-quality Val-Cit-PAB-MMAE and its derived impurities.Moreover, we provide the following technical development services:

Reliable and available kilogram-level supply;
kilogram-level GMP supply in commercial production stage;
Complete DMF registration;
CMC and regulatory affair service(IND, NDA) based on this product.

Product Specifications:purity≥99%, Total Impurities≤1.0%, KF≤1.0%

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