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Description :Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a cytotoxic payload MMAE. Monomethyl Auristatin E(MMAE) functions as a potent mitotic inhibitor by inhibiting tubulin polymerization.Valine-citrulline is a common lysosomally cleavable dipeptide. PAB is a typical self-immolative spacer.
We can provide high-quality Val-Cit-PAB-MMAE and its derived impurities.Moreover, we provide the following technical development services:
Reliable and available kilogram-level supply;
kilogram-level GMP supply in commercial production stage;
Complete DMF registration;
CMC and regulatory affair service(IND, NDA) based on this product.
Product Specifications:purity≥99%, Total Impurities≤1.0%, KF≤1.0%
All our products are only used for scientific research, registration and application research to obtain approval from the drug regulatory authority, and the manufacturing of drugs that have been approved for marketing by the drug regulatory authority. We do not provide products and services for any personal use